Cardiometabolic Lab
The Cardiometabolic Laboratory (CML) is situated in the School of Education and Applied Sciences at the University.
What do we do?
The Cardiometabolic Laboratory (CML) is situated in the School of Education and Applied Sciences at the University. The lab is interested in several themes of enquiry associated with cardiometabolic heath, including:
- Modifiable lifestyle interactions with cardiometabolic health
- The epidemiology of cardiometabolic health
- The development of non-invasive methodologies for determining cardiometabolic health.
Meet the team
Simon is a Senior Lecturer in Sport & Exercise Physiology at University of Gloucestershire, UK. Simon has been a lecturer for over 15 years and has taught in both the UK and New Zealand; he is a very experienced postgraduate supervisor having seen 6 PhD and 5 MSc research students through to completion. Simon is currently supervising 5 PhD students who have research interests in a variety of areas associated with sedentary behaviour, physical activity, and cardiovascular physiology. Simon is an advocate of strong academic collaboration and as such has an extensive research profile with over peer-reviewed 100 research articles associated with exercise physiology.
Cardiometabolic Laboratory Director – Dr Simon Fryer
Louise is a Senior Lecturer in Exercise Physiology and Nutrition at University of Gloucestershire. Following her undergraduate (BSc Hons in Sport and Exercise Science) and postgraduate studies (MSc in Exercise Physiology), Louise obtained a PhD in Human and Exercise Physiology (Human Performance) focusing on the cardiorespiratory responses and limitations to exercise. She then completed a post-doctoral position exploring the role of exercise and nutrition on cardiovascular health, exercise tolerance and cognitive function. As an academic with over 15 years of experience in research and teaching, Louise has also supervised MSc and PhD students in these areas.
Louise’s research focus is on cardiorespiratory physiology; in particular the interactions between the cardiovascular and respiratory systems in health and disease and the implications on exercise tolerance and performance. One key area of this research aims to understand the cardiovascular consequences of increased respiratory demand during exercise and how training can attenuate the metabolic cost of respiratory muscle work to influence exercise tolerance. A second area focuses on exploring the role of modifiable lifestyle factors such as diet, nutrition and physical activity on cardiovascular and respiratory health and exercise tolerance. Louise was previously awarded the American College of Sports Medicine – Gatorade Sport Science Institute Sport Nutrition Award for work investigating the effect of meal(s) and fluid ingestion on airway health.
Cardiometabolic Laboratory Faculty Member – Dr Louise Turner
Anne is a Lecturer in Physiotherapy in the School of Health and Social Care at University of Gloucestershire, UK. She has been qualified as a Physiotherapist for over 30 years and gained a Master of Applied Science (Manipulative Physiotherapy), from the University of South Australia and a PhD in Physiotherapy from the University of East Anglia.
Clinically, Anne specialises in musculoskeletal and chronic pain rehabilitation and appreciates the evidence-based role that physical activity and reducing sedentary behaviour has on recovery. In fact, physical activity and exercise are the most clinically and cost-effective ways of managing virtually every chronic disease.
Anne’s research interests encompass promoting physical activity and reducing sedentary behaviour within specific populations such as menopausal women. The menopause is a natural physiological transition affecting women between 39-59 years of age, and physical activity is thought to play a protective role in reducing menopausal symptoms and improve the quality of life of women during midlife.
Whilst most people appreciate the health benefits of physical activity and reducing sedentary behaviour, this does not always translate to action. Using participatory mixed-methods research designs, the physiology of, and the beliefs and attitudes towards, physical activity and sedentary behaviour can be married in order to inform interventions which are behaviourally adoptable by the population of interest.
Cardiometabolic Laboratory Faculty Member – Dr Anne Daykin
With a background in exercise physiology and experience in assessing health outcomes, I am primarily interested in the interaction between lifestyle behaviours and cardiovascular disease risk, including diet and physical activity, but particularly sedentary behaviours. My expertise has supported both experimental and public health research, and I have extensive experience in conducting cardiovascular health and function measurements in both clinical (coronary heart disease, stroke, pregnancy) and non-clinical populations. A second research interest, which facilitates our sedentary behaviour research, is the development of non-invasive tools for the assessment of cardiovascular health and determination of disease risk. I enjoy understanding methodological components, including measurement device assumptions (precision and accuracy) and how to interpret the physiological signals. I have identified novel approaches for the reliable and accurate monitoring of the effects of sedentary behaviour on the cardiovascular system, whilst also determining their use in large-scale epidemiological studies in aiding cardiovascular risk stratification.
Cardiometabolic Laboratory Affiliate Member – Dr Keeron Stone
Having spent many years as a practising physiotherapist in the NHS, Eve Scarle joined University of Gloucestershire in 2006 as a lecturer. In recent years Eve developed and led a number of academic courses in Allied Health. Eve has a keen interest in how exercise and physical activity can be used to improve health and prevent, or treat chronic diseases. Eve coordinates a range of rehabilitation programmes such as cardiac rehabilitation that are run at Oxstalls Campus. Eve is currently undertaking her Professional Doctorate in Sport & Exercise Sciences with a focus on the effects of prolonged uninterrupted and interrupted sitting on cardiovascular function in patients with established coronary heart disease.
Cardiometabolic Faculty Member/Doctoral Student – Eve Scarle
Craig is an exercise physiologist primarily interested in the interactions between modifiable lifestyle behaviours, primarily sedentary behaviour, and cardiovascular disease risk. Craig has experience leading and supporting experimental research primarily focussed on cardiovascular health and function in both clinical and non-clinical populations. Craig’s second research interest focuses on research methods and synthesis. During his time at the University of Gloucestershire, Craig also worked as an assistant in the University of Gloucestershire Performance Lab providing physiological performance testing and support to a range of professional and recreational athletes.
Having completed his PhD at the University of Gloucestershire, Craig is now undertaking a Post-Doctoral Research Fellowship at the prestigious University of North Carolina at Chapel Hill investigating the physiological mechanisms of prolonged sitting-induced cardiovascular dysfunction.
Cardiometabolic Laboratory Affiliate Member – Dr Craig Paterson
Arsalan Moinuddin is a PhD researcher at University of Gloucestershire – Oxstalls campus, Gloucester. Working under the supervision of Dr. Simon Fryer, Dr Keeron Stone, and Dr Louise Turner, his research centers on examining the impact of uninterrupted prolonged sitting and physical activity interruption during prolonged sitting on cardiovascular health.
He has received his undergraduate Medicine degree (M.B.B.S) from Al-Ameen Medical College, Bijapur, India and performed his residency training in Medical Physiology (M.D.) from the Himalayan Institute of Medical Sciences in Dehradun, India. He has an MPh. from the University of Glasgow in Scotland and a MSc. in Kinesiology from Texas Tech University in Lubbock, U.S.A where he has also served as a graduate teaching instructor. Arsalan was an Assistant Professor in the Department of Physiology at a several of medical schools in India. His educational background in medical physiology and prior experience of working in a vascular function lab during his M.S. (Kinesiology), provided him a smooth transition into the field of vascular health research.
Cardiometabolic Laboratory PhD Student – Arsalan Moinuddin
Jonathon is a health enthusiast, gym manager and personal trainer, training semi-professional sports teams and triathletes. After graduating with a BSc Sport and Exercise Sciences degree, he is continuing his study at University of Gloucestershire with an research MSc in Applied Sport and Exercise Science within the Cardiometabolic Laboratory.
Under the supervision of Dr. Simon Fryer and Dr Louise Turner, Jonathon is looking to determine a more sustainable physical activity strategy for sedentary populations, to counteract the detrimental effects of prolonged sitting on arterial health, with the end aim of reducing cardiovascular risk in inactive individuals.
Cardiometabolic Laboratory Student – Jonathan Atkinson
David is an MSc Applied Sport and Exercise Science research student in the Cardiometabolic Laboratory at University of Gloucestershire. David has recently graduated with a BSc Sport and Exercise Sciences degree and is currently exploring the impact of poor diet and sedentary behavior on cardiovascular and respiratory systems of young healthy male and females. Under the supervision of Dr Louise Turner and Dr Simon Fryer, David’s aim is to understand in detail how modifiable lifestyle factors impact physiological mechanisms during an acute bout of prolonged sitting coupled with a high-fat meal.
David is a keen road racing cyclist who has previously raced nationally in the UK. Having always understood the benefits of exercise, he hopes to continue his understanding of exercise physiology within a clinical setting to reduce detrimental effects associated with poor modifiable lifestyle choices, while sharing his understanding of physiology with others. David enjoys academia and healthcare and his long-term aspiration is to conduct high quality research and teaching within the context of sport and exercise science.
Cardiometabolic Laboratory Student – David Spreadbridge
Research
The cardiometabolic lab team work on a wide range of projects at any one time, at the moment the team are researching the following:
- The effects of uninterrupted and interrupted sitting on cardiovascular function in patients with established coronary heart disease.
- The effects of uninterrupted and interrupted sitting on cardiovascular, cerebrovascular, and executive functions in patients with long COVID syndrome.
- The effects of leg fidgeting on the cardiovascular, cerebrovascular, and executive functions during prolonged sitting following a high fat meal in healthy adults.
- The effects of prolonged sitting and a high fat meal on pulmonary and vascular function in healthy adults.
- The effects of habitual physical activity and cardiorespiratory fitness on the cardiovascular response to prolonged sitting.
- The effects of sedentary behaviour on biomarkers of inflammation and cardiovascular risk and morbidity.
- The effects of intermittent fasting on the cardiovascular response to prolonged uninterrupted and interrupted sitting.
- The effects of uninterrupted and interrupted sitting on cardiovascular function during pregnancy.
- Determining mechanism-informed, socioecological-based sedentary behavior substitution recommendations to mitigate cardiovascular risk.
- Short-term prognostic impact of the aortic-femoral arterial stiffness gradient in older adults without prevalent cardiovascular disease: The Atherosclerosis Risk in Communities (ARIC) Study.
For a full list of publications, please view individual member ResearchGate profiles in team biographies above.
Resources and affiliates
Resources
Affiliates
Contacts
Cardiometabolic Laboratory Director, Dr Simon Fryer: [email protected]
Cardiometabolic Laboratory Faculty Member, Keeron Stone: [email protected]
Cardiometabolic Laboratory Faculty Member, Dr Louise Turner: [email protected]
Oxstalls Campus, Longlevens, Gloucester, Gloucestershire, GL2 9HW